CRISPR/Cas9 and TALE: beyond cut and paste

Subjects: Biology >> Biophysics >> Cell Biology submitted time 2016-05-12

Deng, Liping Ren, Ruotong Liu, Guang-Hui Wu, Jun Suzuki, Keiichiro Belmote, Juan Carlos Izpisua Liu, Guang-Hui Liu, Guang-Hui

Abstract： Nuclease-based genome editing has proven to be a powerful and promising tool for disease modeling and gene therapy. Recent advances in CRISPR/Cas and TALE indicate that they could also be used as a targeted regulator of gene expression, as well as being utilized for illuminating specific chromosomal structures or genomic regions.

Peer Review Status:Awaiting Review

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